What is a primary treatment for malignant hyperthermia?

What is a primary treatment for malignant hyperthermia?

• A. IV epinephrine
• B. IV dantrolene sodium
• C. IV atropine
• D. IV calcium gluconate

Answer: (B)

The primary treatment for malignant hyperthermia is intravenous dantrolene sodium. Malignant hyperthermia is a life-threatening condition that can occur during anesthesia, characterized by a rapid increase in body temperature and severe muscle contractions. Dantrolene sodium works by directly acting on the skeletal muscle cells to reduce calcium release from the sarcoplasmic reticulum, which effectively helps to control the symptoms of this condition. Dantrolene is the only specific antidote for malignant hyperthermia, and it plays a critical role in managing the metabolic disturbances associated with the excessive calcium release that occurs in this condition. Administering dantrolene helps to rapidly decrease muscle hypermetabolism and restore normal body temperature, thus addressing the acute symptoms of malignant hyperthermia effectively. Other options offered would not have the same efficacy in treating malignant hyperthermia. For example, while IV epinephrine may be used in a different context such as severe allergic reactions or cardiac arrest, it does not address the underlying cause of malignant hyperthermia. Similarly, IV atropine is primarily an anticholinergic that is used to treat bradycardia and does not have a role in managing this particular syndrome. IV calcium gluconate is utilized in conditions

The primary treatment for malignant hyperthermia is intravenous dantrolene sodium. Malignant hyperthermia is a life-threatening condition that can occur during anesthesia, characterized by a rapid increase in body temperature and severe muscle contractions. Dantrolene sodium works by directly acting on the skeletal muscle cells to reduce calcium release from the sarcoplasmic reticulum, which effectively helps to control the symptoms of this condition.

Dantrolene is the only specific antidote for malignant hyperthermia, and it plays a critical role in managing the metabolic disturbances associated with the excessive calcium release that occurs in this condition. Administering dantrolene helps to rapidly decrease muscle hypermetabolism and restore normal body temperature, thus addressing the acute symptoms of malignant hyperthermia effectively.

Other options offered would not have the same efficacy in treating malignant hyperthermia. For example, while IV epinephrine may be used in a different context such as severe allergic reactions or cardiac arrest, it does not address the underlying cause of malignant hyperthermia. Similarly, IV atropine is primarily an anticholinergic that is used to treat bradycardia and does not have a role in managing this particular syndrome. IV calcium gluconate is utilized in conditions